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Cariogenicity of mutants of Streptococcus mutans
Journal of Dental Research
|October 1, 1980
Abstract:
In this study, we induced a number of mutants of S. mutans differing in their abilities to synthesize glucan and produce acid. When tested for cariogenicity in gnotobiotic rats, "high pH" mutants caused less caries, but could not supplant a cariogenic parent strain.
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