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Related Experiment Videos

Case report: candida infection presenting as laryngitis.

R Lawson, G Bodey, M Luna

    The American Journal of the Medical Sciences
    |November 1, 1980
    PubMed
    Summary
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    Hoarseness can be an early sign of Candida infection in acute leukemia patients. Early investigation and antifungal treatment are crucial for managing this opportunistic infection.

    Area of Science:

    • Infectious Diseases
    • Hematology
    • Otolaryngology

    Background:

    • Acute leukemia patients are immunocompromised, increasing susceptibility to opportunistic infections.
    • Candida infections can manifest in various ways, including invasive forms.
    • Laryngeal involvement by Candida is a rare but serious complication.

    Observation:

    • Three acute leukemia patients presented with hoarseness as the initial symptom.
    • Hoarseness was attributed to laryngeal candidiasis in these cases.
    • Two patients later developed systemic candidiasis, indicating disseminated infection.

    Findings:

    • Hoarseness can be a presenting sign of laryngeal candidiasis in acute leukemia.
    • Early diagnosis of laryngeal candidiasis is essential for prompt management.

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  • Systemic candidiasis risk is elevated in these patients.
  • Implications:

    • Clinicians should consider laryngeal candidiasis in acute leukemia patients with hoarseness.
    • Investigation for fungal infection, including laryngeal examination, is recommended.
    • Systemic antifungal therapy should be considered for suspected or confirmed cases.