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Haloperidol -- its use in children.

A C Serrano

    The Journal of Clinical Psychiatry
    |April 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Haloperidol effectively treats psychotic symptoms in children with autism and schizophrenia. It also helps manage Tourette's syndrome and behavioral issues in hyperactive children, improving their response to therapy.

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    Area of Science:

    • Child and Adolescent Psychiatry
    • Pediatric Neurology
    • Clinical Pharmacology

    Background:

    • Psychotic symptoms and behavioral disturbances present significant challenges in pediatric populations.
    • Limited pharmacological options exist for conditions like childhood autism, schizophrenia, Tourette's syndrome, and hyperactive disorders.

    Purpose of the Study:

    • To evaluate the safety and efficacy of haloperidol in children for various psychiatric and neurological conditions.
    • To assess haloperidol's utility in nonpsychotic, hyperactive, or aggressive children.

    Main Methods:

    • Clinical assessment of symptom relief and behavioral control.
    • Gradual dose titration to minimize side effects.
    • Monitoring for adverse events, particularly drowsiness and extrapyramidal symptoms.

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    Main Results:

    • Haloperidol demonstrated safety and efficacy in alleviating psychotic symptoms in children with autism and schizophrenia.
    • It proved effective for Tourette's syndrome and beneficial in managing acute episodes in hyperactive or aggressive children.
    • Patients exhibited improved calmness and responsiveness to other therapies and educational instruction.

    Conclusions:

    • Haloperidol is a well-tolerated and effective treatment option for psychotic symptoms in children.
    • It offers a valuable therapeutic alternative for Tourette's syndrome and behavioral dysregulation in pediatric patients.
    • The drug enhances treatment response and educational engagement in affected children.