Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Nonspecific vaginosis

K K Holmes, C Spiegel, A R Amsel

    Scandinavian Journal of Infectious Diseases. Supplementum
    |January 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Morphological micro-computed tomography assessment of cleaned freeze-dried compacted cancellous bone allografts.

    Bone·2026
    Same author

    Beyond the Field of View: Enhancing Detection of Orthopaedic Metastases in Cancer Staging.

    Acta orthopaedica Belgica·2026
    Same author

    Beyond the germ: Rethinking implant-related infections as a host-microbiota-biomaterial ecosystem.

    Biofilm·2026
    Same author

    A large chest wall tumour in an asymptomatic 15-year-old girl.

    BMJ case reports·2025
    Same author

    [Investigation and analysis of occupational disease risk assessment index system in the automotive repair industry].

    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases·2025
    Same author

    Ice sheet-free West Antarctica during peak early Oligocene glaciation.

    Science (New York, N.Y.)·2024

    Nonspecific vaginosis (NSV) is a common condition characterized by vaginal discharge. Metronidazole is the most effective treatment, though optimal dosage and partner treatment need further research.

    Area of Science:

    • Gynecology
    • Microbiology
    • Clinical Medicine

    Background:

    • Nonspecific vaginosis (NSV) is a prevalent clinical syndrome.
    • Characterized by a thin, grey, malodorous vaginal discharge with a pH > 4.5.
    • Microbiologically, it involves a shift from lactobacillus dominance to Gardnerella vaginalis and anaerobic bacteria.

    Purpose of the Study:

    • To describe the clinical, biochemical, and microbiologic features of NSV.
    • To evaluate the efficacy of different antimicrobial treatments for NSV.

    Main Methods:

    • Clinical examination for characteristic discharge and clue cells.
    • Biochemical analysis of vaginal discharge (pH, amine detection).
    • Microbiologic assessment of vaginal flora.

    Related Experiment Videos

    Main Results:

    • NSV discharge has a pH > 4.5, a fishy odor, and clue cells.
    • Increased concentrations of amines and volatile organic acids are present.
    • Ampicillin shows some efficacy, but metronidazole is the most effective antimicrobial.

    Conclusions:

    • Metronidazole is the most effective antimicrobial for nonspecific vaginosis.
    • Further studies are needed to determine optimal metronidazole dosage and the necessity of treating sexual partners.