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Updated: Aug 10, 2026

Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation
Published on: April 14, 2016
Aspects of renal bone disease
Abstract:
In advanced chronic renal failure hypocalcaemia can be due to a combination of factors. These include decreased delivery of calcium into the plasma and increased renal tubular leakage of calcium. The secondary hyperparathyroidism that follows the hypocalcaemia leads to osteosclerosis, probably by movement of cortical mineral into trabecular bone. In the dialysis population, an atypical and readily identifiable form of osteomalacia sometimes occurs and is probably secondary to a water-borne toxin.
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