17p+ in a patient with chronic myelogenous leukemia (CML): its differentiation from an isochromosome 17,[i(17q)]

Bone marrow chromosomes are usually of such poor quality as to make it difficult to band them with QFQ or GTG techniques. Because of the possibility that many nonrandom chromosomal abnormalities are present in hematologic disorders, a more reliable banding technique is necessary. Using the RFA technique an abnormality thought to be isochromosome 17, [i(17q)] in a patient with chronic myelogenous leukemia, was revealed to be 17 p+.