Features of prostatic sarcomas in combined aspiration and punch biopsies

Of malignant prostatic tumors, 0.1% to 0.2% are believed to be sarcomas; about 30% of these are observed in the first decade of life. We present the morphologic findings in three patients aged 55 to 70 years in whom an osteosarcoma and two leiomyosarcomas were demonstrated by combined aspiration and punch biopsies. The sarcomas clearly differed cytologically from the various forms of prostatic carcinoma. Some difficulties in the distinction of pleomorphic tumor cells of leiomyosarcomas from pleomorphic epithelial cells from the seminal vesicle may occur. One fibrosarcoma was diagnosed by punch biopsy alone in a 57-old-year patient. The incidence of sarcomas in our material was 0.17% of all malignant tumors of the prostate.