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Updated: Aug 11, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
A balanced oral sedation technique
Abstract:
The results of the preliminary clinical investigation for treating ambulatory patients in a nonhospital environment offer the following advantages of the regimen discussed: A high degree of predictability, with a wide margin of safety, when utilized properly. All of the patient's vital signs remained stable, although respiratory rate and depth were depressed for short periods of time. Adequate working time to perform all phases of pedodontic dentistry, with a minimum amount of postoperative nausea. A smooth onset of action and a good experience of young patients who were confronted with a stressful situation. Profound local anesthesia is mandatory, otherwise painful stimuli will awaken the patient and result in a stormy encounter. The personality and experience of the dental personnel contributed a great deal to the smoothness and success of the procedure.
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