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Use of penicillin and nafcillin discs as an aid to identification of Pasteurella multocida
Journal of Medicine
|January 1, 1981
Abstract:
Strains of Pasteurella multocida isolated from children and animal sources were studied by means of the Kirby-Bauer disc method and were found to be highly susceptible to penicillin G and resistant to nafcillin. It is suggested that these tests may be of aid in the preliminary identification of this pathogen.
Insights
Pasteurella multocida strains from humans and animals show high susceptibility to penicillin G but resistance to nafcillin. These antibiotic profiles may help in preliminary identification of this bacterial pathogen.
Area of Science:
- Microbiology
- Bacteriology
- Antimicrobial Susceptibility Testing
Background:
- Pasteurella multocida is a significant bacterial pathogen.
- It causes infections in both animals and humans.
- Understanding its antimicrobial resistance patterns is crucial for effective treatment.
Purpose of the Study:
- To investigate the antibiotic susceptibility profiles of Pasteurella multocida strains.
- To evaluate the potential of antibiotic resistance patterns for preliminary pathogen identification.
Main Methods:
- Bacterial isolates of Pasteurella multocida were obtained from human and animal sources.
- The Kirby-Bauer disc diffusion method was employed for antimicrobial susceptibility testing.
Main Results:
- All studied Pasteurella multocida strains exhibited high susceptibility to penicillin G.
- Conversely, the strains demonstrated resistance to nafcillin.
Conclusions:
- The distinct antibiotic susceptibility patterns, specifically high susceptibility to penicillin G and resistance to nafcillin, can aid in the preliminary identification of Pasteurella multocida.
- This finding supports the use of antimicrobial susceptibility testing as a rapid diagnostic tool for this pathogen.