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A pigmented calcifying odontogenic cyst

J V Soames

    Oral Surgery, Oral Medicine, and Oral Pathology
    |April 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    This study reports a rare pigmented calcifying odontogenic cyst in a young West Indian female. Ultrastructural analysis revealed melanin pigment distribution within cyst cells, offering insights into this rare condition.

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    Area of Science:

    • Oral pathology
    • Odontogenic cysts
    • Melanin pigmentation

    Background:

    • Calcifying odontogenic cysts (COCs) are rare jaw cysts.
    • The pigmented variant of COC is exceptionally uncommon.
    • Understanding the cellular basis of pigmentation in COCs is important for diagnosis.

    Observation:

    • A case of pigmented COC occurred in a 15-year-old West Indian girl.
    • Melanin pigment was widespread, notably in stellate reticulum-like cells.
    • Ultrastructural examination showed abundant melanosomes in these cells.

    Findings:

    • Epithelial ghost cells within the cyst contained dense tonofilament bundles.
    • Melanocytes were identified, with two distinct forms based on melanosome development.
    • Melanin distribution varied, with fewer melanosomes in ghost cells compared to stellate reticulum cells.

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    Implications:

    • This case expands the understanding of pigmented COC variations.
    • Histopathological and ultrastructural findings provide insights into melanin synthesis and deposition in odontogenic cysts.
    • Further research may clarify the pathogenesis and clinical significance of pigmented COCs.