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Photosensitivity in childhood

C T Jansén

    Acta Dermato-Venereologica. Supplementum
    |January 1, 1981
    PubMed
    Summary

    Childhood-onset photosensitivity disorders affect 26% of patients, with polymorphous light eruptions (PMLE) being most common. Early-onset PMLE often presents with prurigo-like or vesicopapular rashes.

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    Area of Science:

    • Dermatology
    • Photobiology

    Background:

    • Photosensitivity disorders can manifest in childhood.
    • Understanding the onset and characteristics of pediatric photodermatoses is crucial for diagnosis and management.

    Purpose of the Study:

    • To investigate the prevalence and clinical features of photosensitivity disorders with onset in childhood (age 15 or younger).
    • To identify common photodermatoses presenting in pediatric populations.

    Main Methods:

    • Retrospective analysis of 370 patients diagnosed with photosensitivity disorders.
    • Categorization of patients based on age of onset and specific photodermatosis.
    • Classification of rash morphology in polymorphous light eruptions (PMLE).

    Main Results:

    • 26% (95/370) of patients experienced photosensitivity onset by age 15.
    • Polymorphous light eruptions (PMLE) were the most frequent diagnosis in this cohort (78 cases).
    • Childhood-onset PMLE commonly presented with prurigo-like (50%) or vesicopapular (25%) rash morphologies. Other diagnoses included xeroderma pigmentosum, erythropoietic protoporphyria, systemic lupus erythematosus, and pellagra. No cases linked to external chemicals or medications were found.

    Conclusions:

    • Photosensitivity disorders frequently begin in childhood, with PMLE being a primary concern.
    • Specific rash morphologies are characteristic of childhood-onset PMLE.
    • Rare genetic and systemic conditions, alongside PMLE, constitute the spectrum of childhood photodermatoses.

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