Neurophysiological measurement of pain

Neurophysiological measurement of pain is a research goal rather than a reality today. The gap may be narrowed by combining different techniques. Electrophysiological methods with stimulation and recording directly from the afferent pathway should contribute to a more specific and differentiated picture of the mode of action of analgesics, as a basis for development of new therapies. Such electrophysiological methods can be combined with behavioural studies, both in humans and in animal pain models.