The giant cell fibroma. A review of 464 cases

The biopsy service at Indiana University School of Dentistry, Department of Oral Pathology, accessioned 464 cases of giant cell fibroma from February, 1971, until May, 1980. From a study of these cases, it appears that the giant cell fibroma is a distinctive lesion with a characteristic age distribution, location, sex incidence, and histologic appearance. Clinically, the giant cell fibroma presents as an asymptomatic, papillary, pedunculated lesion, commonly regarded as a papilloma. It is fairly common in young persons and usually occurs on the gingiva. No sex predilection has been noted, and simple surgical excision appears to be the treatment of choice.