[Analytical study of the diffusion capacity of the lungs in patients with chronic renal insufficiency]

The analytical diffusion capacity of the lungs was determined in 63 patients with various stages of chronic renal insufficiency. On the base of the values of serum creatinine and glomerular filtration the patients were subdivided into four groups. Considerable changes in all the three values of alveolar-capillary diffusion (DLCO, Dm, Vc) were established, with a definite parallelism between those changes and the chronic renal insufficiency stage. The most serious changes concern the membrane component. The correlation analysis confirms the presence of high reverse correlation interdependence, both with the values of serum creatinine and blood urea and with the diastolic arterial pressure.