An electroaerosol device for group vaccination against influenza

With the aid of an electroaerosol device a group of persons were vaccinated by inhalation of influenza vaccine. In a first trial 76 persons with a low antibody level (1 : 20 and less) were vaccinated against A2/Victoria/1/72 and B/USSR/69: Antibodies were reexamined 30 days later, Interferon at the 3rd and 10th day. This kind of vaccination caused an antibody increase statistically significant. In the course of an influenza epidemic 2,300 persons vaccinated by inhalation were compared with 2,195 not vaccinated. Among the persons vaccinated there were 13.7 +/- 0.7% diseases, among the non vaccinated persons 26.3 +/- 0.9%.