[Local application of prostaglandin F2 alpha to primigravid interruption patients in first trimester]

A comparison was made between three methods of local prostaglandin F2 alpha application for medicamentous induction of interruption in 375 primigravidae in the first trimester. They were extra-amniotic transcervical application, intracervical instillation of gel, and intracervical application, using a portio adaptor according to Fikentscher/Semm. Retrospective and prospective analyses were made of 125 unselected patients for each of the three methods, and the portio adaptor technique proved to be most effective of all with regard to non-invasive cervix dilatation. This method, when compared to others, was found to be best acceptable to patients and medical personnel alike, with no risk of subsequent ascending infection and with lowest prostaglandin consumption.