Psoriasis vulgaris and pustulosis palmaris et plantaris and the HLA system

The frequency of locus A and B antigens in 39 patients with pustulosis palmo-plantaris and in 16 patients with psoriasis vulgaris was determined in comparison with a control group of 394 healthy subjects. The data obtained in the psoriasis vulgaris group confirmed the literature data (increased frequency of B 13 and B 17 antigens). In the pustulosis palmo-plantaris group only the patients with the histopathologically confirmed psoriasis pustulosa showed a statistically significant increase of B 12 antigen which has not been reported so far.