Two cases of incompatibility to carbon-coated subperiosteal implants

Two cases of clinical incompatibility of carbon-coated subperiosteal implants are presented. The clinical history and the microscopic features of biopsy material of each case are reviewed. The histologic appearance of tissue from both cases presented scattered particles of carbon surrounded by lymphocytes, macrophages, plasma cells, and tissue eosinophils. Active phagocytosis and Russell's bodies were seen. Large masses of carbon were surrounded by connective tissue. The clinical and microscopic findings suggest an immunologic rejection of the implant-coating material.