A scanning electron microscopic study of leukocytes and their interaction with bacteria in human periodontitis

Shape, size, topographical relationships, surface morphology, phagocytosis and locomotion were used to identify and study leukocytes in human cases of periodontitis. These cells were described in the following locations: in peripheral blood vessels adjacent to the pocket epithelium; gingival connective tissue; basement lamina; sectioned pocket epithelium; surface of pocket epithelium; junctional epithelium; and cementum surface. The interaction of leukocytes and bacteria was documented in the phases of recognition, attachment and engulfment of bacteria. Morphologic data suggesting the process of degranulation was also presented.