CAP, HCS and urinary oestriol assays in diabetic pregnancy

The value of serial estimations of plasma CAP, HCS and urinary oestriol assays in pregnancies complicated with diabetes has been studied. The material consists of 31 patients, 16 of whom delivered normal infants and 15 delivered newborns with diabetic foetopathy. It is concluded that the levels of CAP, HCS and urinary oesteriol excretion in diabetic pregnancies are comparable to those found in normal pregnancy. No significant differences in the biochemical parameters were detected between diabetic women who delivered infants with foetopathy compared to diabetic women who delivered normal infants. The maternal oestriol excretion was, however, somewhat higher in diabetic women who delivered infants with macrosomia.