Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Antimalarials in rheumatic diseases

R O Day, P Sambrook, G D Champion

    Australian and New Zealand Journal of Medicine
    |December 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Trans-Tasman Comparison of Microbial Trends and Antibiotic Resistance Patterns in Severe Odontogenic Infection: A 5-Year Retrospective Analysis of South Australia, Australia and Auckland, New Zealand.

    Australian dental journal·2026
    Same author

    The role of hyperbaric oxygen in osteoradionecrosis-a prophylactic insight.

    Australian dental journal·2023
    Same author

    Factors affecting surgical mortality of oral squamous cell carcinoma resection.

    International journal of oral and maxillofacial surgery·2020
    Same author

    Comparing antibiotic adjuncts in periodontitis.

    Australian dental journal·2019
    Same author

    The financial burden of acute odontogenic infections: the South Australian experience.

    Australian dental journal·2019
    Same author

    Mandibular advancement splints for obstructive sleep apnoea - a cautionary tale.

    Australian dental journal·2019
    Same journal

    Gastroenterological Society of Australia, Annual Scientific Meeting, May 1980.

    Australian and New Zealand journal of medicine·2020
    Same journal

    'A touch of sugar'--a dangerous euphemism still alive and well.

    Australian and New Zealand journal of medicine·2001
    Same journal

    Silent myocardial ischaemia following methysergide overdose.

    Australian and New Zealand journal of medicine·2001
    Same journal

    Extensive jugular and upper limb thrombosis in a patient with factor V Leiden mutation and non-Hodgkin's lymphoma.

    Australian and New Zealand journal of medicine·2001
    Same journal

    Visual loss as the presenting feature of giant cell arteritis.

    Australian and New Zealand journal of medicine·2001
    Same journal

    Lymphoproliferative disease causing angioedema--an uncommon association.

    Australian and New Zealand journal of medicine·2001
    See all related articles

    Antimalarial drugs are effective for rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) when used with careful dosage control and eye monitoring. This approach minimizes risks, making them a viable treatment option for rheumatic diseases.

    Area of Science:

    • Rheumatology
    • Ophthalmology
    • Pharmacology

    Background:

    • Antimalarial drug use in rheumatic diseases like rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) has decreased due to toxicity concerns and perceived ineffectiveness.
    • This decline overlooks the established benefits and manageable risks associated with these medications.

    Purpose of the Study:

    • To re-evaluate the efficacy and safety of antimalarials in treating rheumatic conditions.
    • To address the declining use by highlighting evidence of effectiveness and strategies to mitigate adverse effects.

    Main Methods:

    • Review of recent literature and clinical evidence regarding antimalarial use in RA and SLE.
    • Analysis of data on retinal toxicity and risk management strategies.

    Related Experiment Videos

    Main Results:

    • Strong evidence supports the efficacy of antimalarials in managing RA.
    • Strict adherence to controlled daily dosages and regular ophthalmological surveillance significantly reduces the risk of serious retinal toxicity.

    Conclusions:

    • Antimalarials remain effective treatments for RA and SLE.
    • Careful patient management, including dosage control and eye examinations, can ensure the safe use of these drugs in rheumatic disease therapy.