Do breast and bottle fed babies require vitamin supplements?

In the present stage of knowledge, the following approach to vitamin supplementation seems reasonable. Breast-fed full-term infants should be supplemented with vitamin D (400 I.U./day). Supplementation of bottle-fed infants will depend upon the vitamin content of the formula which is being used. Pre-term and LBW infants may need higher amounts of vitamin D (800-1 000 I.U./day) and should be supplemented with vitamin E (1-2 I.U./day), C (50 mg/day), B6 (30-60 mcg/day) and folic acid (50-100 mcg/day) when they are being fed formulas with high amounts of PUFA and proteins or with iron. Multivitamin supplementation appears to be acceptable for infants of very low birth weight (less than 1 500 g) until they reach a body weight of at least 2 000 grams or a caloric intake of 300 kcal/day. Finally, the present routine of administering 0.5-1.0 mg of vitamin K at birth to all infants should be continued.