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Related Experiment Videos

A viscoelastic model for use in predicting arterial pulse waves

R Holenstein1, P Niederer, M Anliker

  • 1Institute of Biomedical Engineering, University of Zurich, Switzerland.

Journal of Biomechanical Engineering
|November 1, 1980
PubMed
Summary

This study introduces a novel method to model arterial wall viscoelasticity, improving the accuracy of mathematical models for arterial pulse propagation. The findings enhance predictions of pressure and flow pulses, particularly in the distal circulation.

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Area of Science:

  • Biomedical Engineering
  • Computational Fluid Dynamics
  • Cardiovascular Physiology

Background:

  • Previous nonlinear mathematical models of arterial circulation often neglected or oversimplified vessel wall viscoelasticity.
  • Accurate modeling of arterial wall properties is crucial for understanding cardiovascular dynamics.

Purpose of the Study:

  • To develop and validate a new method for simulating nonlinear viscoelastic properties of arterial walls.
  • To investigate the influence of arterial wall friction on pulse wave propagation using a mathematical model.

Main Methods:

  • A convolution integral of the creep function and pressure history was employed to simulate nonlinear viscoelasticity.
  • The developed simulation was integrated into a mathematical model of arterial pulse propagation.

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  • Model predictions were compared with in-vivo measurements, focusing on distal circulation.

    • Main Results:

    • The proposed method accurately describes measured characteristics of arterial viscoelasticity.
    • The model incorporating viscoelasticity showed significantly improved agreement with in-vivo measurements compared to models without it.
    • Internal wall friction was found to influence the shape, amplitude, and mean value of pressure and flow pulses.

    Conclusions:

    • The novel simulation method effectively captures arterial wall viscoelasticity.
    • Incorporating viscoelasticity in mathematical models leads to more accurate predictions of arterial pulse propagation, especially distally.
    • This approach enhances the understanding of cardiovascular mechanics and provides a more realistic simulation of blood flow dynamics.