Double-tracer, multiple-organ transaxial emission computed tomography: improved localization and characterization of radiotracer distributions

Transaxial emission computed tomography (ECT) was performed in dogs with experimentally induced abscesses, using 67Ga and several 99mTc-labeled organ-specific radiopharmaceuticals. Superimposition of 99mTc ECT images onto the 67Ga images gave the precise anatomic location of the abnormal foci of 67Ga uptake, correctly localizing a perinephric abscess, a splenic abscess, and a focus of osteomyelitis. This technique also permits further characterization of regions of decreased activity.