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Immune thrombocytopenia induced by cotrimoxazole
Summary
Cotrimoxazole can cause low platelet counts (thrombocytopenia). This study identified an anti-platelet autoantibody in a patient
Area of Science:
- Pharmacology
- Immunology
- Hematology
Background:
- Cotrimoxazole is linked to thrombocytopenia.
- Previous theories suggested folate metabolism interference or hapten-induced autoantibodies.