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Related Experiment Videos

Myocardial abscesses

H S Kim, D G Weilbaecher, J T Lie

    American Journal of Clinical Pathology
    |July 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Myocardial abscesses, a rare finding in 0.5% of autopsies, often resulted from disseminated sepsis. Candida and Staphylococcus aureus were common culprits, frequently associated with extracardiac infections.

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    Area of Science:

    • Pathology
    • Infectious Diseases
    • Cardiology

    Background:

    • Myocardial abscesses are uncommon cardiac infections.
    • Understanding their incidence and etiology is crucial for clinical management.

    Purpose of the Study:

    • To determine the incidence of myocardial abscesses.
    • To identify common causative organisms and associated conditions.

    Main Methods:

    • Retrospective review of postmortem materials from two teaching hospitals over a 14-year period (1962-1975).
    • Analysis of 12,359 autopsies to identify cases of myocardial abscesses.
    • Histopathological examination and antemortem blood culture data were reviewed.

    Main Results:

    • Sixty-three cases of myocardial abscesses were identified, representing an incidence of 0.5%.

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  • Candida (37%) and Staphylococcus aureus were the most frequent pathogens.
  • Infective endocarditis was present in 20% of cases.
  • Extracardiac abscesses were found in 81% of patients, suggesting disseminated sepsis as a common origin.
  • Frequent primary conditions included surgical issues, malignancy, and alcoholic liver disease.

    • Conclusions:

    • Myocardial abscesses are rare but often linked to disseminated sepsis.
    • Candida and S. aureus are key pathogens.
    • Associated conditions significantly impact patient outcomes.