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B.T.PABA test: a new absorption test

M Miwa, I Senoue, H Watanabe

    The Tokai Journal of Experimental and Clinical Medicine
    |January 1, 1980
    PubMed
    Summary
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    The B.T.PABA test effectively measures pancreatic exocrine function by assessing PABA absorption post-surgery. This simple test correlates well with other absorption tests, aiding in diagnosing digestion-absorption impairment.

    Area of Science:

    • Gastroenterology
    • Diagnostic Medicine

    Background:

    • Pancreatic exocrine insufficiency can result from gastrectomy.
    • Accurate diagnostic tools are needed to assess post-surgical digestive function.

    Purpose of the Study:

    • To evaluate B.T.PABA as a novel absorption test for pancreatic exocrine function.
    • To assess the utility of B.T.PABA in post-gastrectomy patients.

    Main Methods:

    • 1 gram of B.T.PABA was administered with a test meal.
    • Urinary para-aminobenzoic acid (PABA) excretion was measured over 6 hours.
    • B.T.PABA test results were compared with a 131I-labeled albumin absorption test.

    Main Results:

    • Urinary PABA excretion was lower in early post-gastrectomy patients (Billroth I and II) compared to controls.

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  • PABA excretion levels approached normal in patients long after surgery.
  • A significant correlation was found between the B.T.PABA test and the 131I-labeled albumin test.

    • Conclusions:

    • The B.T.PABA test is a simple and effective method for assessing absorption.
    • B.T.PABA can help identify digestion-absorption impairment following gastrectomy.
    • This test offers a valuable tool for evaluating pancreatic exocrine function post-surgery.