Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Temporal bone studies in anencephaly

I Friedmann, J L Wright, P D Phelps

    The Journal of Laryngology and Otology
    |August 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Anencephalic temporal bones reveal significant malformations, including ossicle and cochlea abnormalities. Despite central nervous system absence, inner ear neuroepithelial structures were well-developed, offering insights into Meniere

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Black Hole Spectroscopy and Tests of General Relativity with GW250114.

    Physical review letters·2026
    Same author

    GW250114: Testing Hawking's Area Law and the Kerr Nature of Black Holes.

    Physical review letters·2025
    Same author

    Improving cosmological reach of a gravitational wave observatory using Deep Loop Shaping.

    Science (New York, N.Y.)·2025
    Same author

    Corrigendum to "Nomogram Predicting Bladder Cancer-specific Mortality After Neoadjuvant Chemotherapy and Radical Cystectomy for Muscle-invasive Bladder Cancer: Results of an International Consortium" [Eur Urol Focus 2021;7:1347-54].

    European urology focus·2022
    Same author

    Mentoring from the diverse lens of epidemiologists reveals a dynamic and mutually rewarding relationship.

    Annals of epidemiology·2021
    Same author

    Prospects for observing and localizing gravitational-wave transients with Advanced LIGO, Advanced Virgo and KAGRA.

    Living reviews in relativity·2020
    Same journal

    Prognostic value of gross tumour volume in laryngeal cancer: a systematic review and meta-analysis.

    The Journal of laryngology and otology·2026
    Same journal

    Surgical Management Of Parapharyngeal Vagal Schwannomas: A Systematic Review And Practical Considerations For Approach Selection.

    The Journal of laryngology and otology·2026
    Same journal

    Novel Use of Lieberman Self-Retainers for Nasal Alar Retraction.

    The Journal of laryngology and otology·2026
    Same journal

    Prevalence and recovery of taste dysfunction after stapedectomy in otosclerosis: a clinical study of 320 patients.

    The Journal of laryngology and otology·2026
    Same journal

    Audiological Outcomes in 465 Primary Myringoplasties: Reporting Pitfalls and Lessons Learned.

    The Journal of laryngology and otology·2026
    Same journal

    Design and technical validation of a low-cost, titanium sheet metal TORP (SM-T) for manufacturing and use in LMICs- ERRATUM.

    The Journal of laryngology and otology·2026
    See all related articles

    Area of Science:

    • Otolaryngology
    • Developmental Biology
    • Neuroscience

    Background:

    • Anencephaly is a severe congenital condition characterized by the absence of a major portion of the brain, skull, and scalp.
    • The temporal bone, housing the auditory and vestibular systems, develops complex structures crucial for sensory function.
    • Understanding temporal bone development in congenital anomalies provides insights into normal development and disease pathology.

    Purpose of the Study:

    • To describe the anatomical and histological features of temporal bones in anencephalic individuals.
    • To investigate the development of inner ear structures in the absence of a developed central nervous system.
    • To explore the potential of anencephalic temporal bones as a model for studying inner ear pathologies.

    Main Methods:

    Related Experiment Videos

    • Histological examination of temporal bones from three anencephalic subjects.
    • Detailed anatomical description of ossicles, cochlea, vestibular labyrinth, and internal auditory meatus.
    • Assessment of neuro-epithelial structures and cranial nerves within the temporal bone.

    Main Results:

    • Observed malformations included ossicle abnormalities and Mondini-type cochlear malformations.
    • Evidence of cochlear hydrops, Reissner's membrane collapse, and vestibular labyrinth distension.
    • Rupture and repair of the saccular wall, fibrous obliteration of the internal auditory meatus with reduced neural elements.
    • Well-developed neuro-epithelial structures despite the absence of the central nervous system.
    • Normal development of the geniculate ganglion and facial nerve.

    Conclusions:

    • Anencephalic temporal bones exhibit unique malformations, including inner ear pathologies.
    • The development of neuro-epithelial structures in anencephalics suggests a degree of developmental autonomy.
    • These findings offer a valuable comparative anatomy resource for studying Meniere's disease and sensorineural lesions.