[Characteristics of cellular immune reactions in animals vaccinated with smallpox and ADPT vaccines]

Zhurnal Mikrobiologii, Epidemiologii I Immunobiologii
|July 1, 1980
PubMed

Immunization with absorbed DPT vaccine in 1 or 3 subcutaneous injections, as well as the intradermal or intracardiac immunization of guinea pigs with smallpox vaccine resulted in the accumulation of 0-positive lymphoyctes, determined by the cytotoxic test, in the lymph nodes. On the 7th day after the intracardiac injection of smallpox vaccine in massive doses a sharp decrease in the content of 0-positive lymphocytes was observed. The number of small lymphocytes with surface immunoglobulin receptors detected by immunofluorescence remains unchanged in the animals of all groups at any period of the experiment.

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