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Age-related changes in the cornea

J C Kotulak, T Brungardt

    Journal of the American Optometric Association
    |August 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    This paper details normal, age-related corneal changes throughout life, including curvature and thickness variations. It also covers senescent changes like reduced luster and endothelial cell count, crucial for optometrists.

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    Area of Science:

    • Ophthalmology
    • Optometry
    • Gerontology

    Background:

    • Optometrists must differentiate physiologic from pathologic corneal changes.
    • Age-related corneal alterations occur across the lifespan, not just in senescence.

    Purpose of the Study:

    • To comprehensively review normal, age-related physiologic changes in the human cornea.
    • To detail specific senescent changes affecting corneal structure and function.

    Main Methods:

    • Literature review focusing on age-related corneal physiology.
    • Compilation of documented age-associated corneal alterations.

    Main Results:

    • Identified age-related changes include alterations in corneal curvature, toricity, diameter, asphericity, and thickness.

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  • Documented senescent changes encompass reduced epithelial luster, dellen, microcystic dystrophy, Hudson-Stahli line, crocodile shagreen, Vogt's limbus girdle, increased stromal relucency, cornea farinata, arcus senilis, Hassall-Henle warts, guttata, and reduced endothelial cell count.

    • Conclusions:

    • Understanding these normal age-related corneal changes is essential for accurate clinical assessment by optometrists.
    • Distinguishing physiologic aging from disease is critical for appropriate patient management.