Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cryptococcosis with multiple squamous cell tumors associated with a T-cell defect

P J Heenan, R L Dawkins

    Cancer
    |January 15, 1981
    PubMed
    Summary

    A severe T-cell defect caused an unusual bone infection with a rare fungus (cryptococcosis) and aggressive skin tumors in a 54-year-old man.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Adipose invasion of muscle in Wagyu cattle: Monitoring by histology and melting temperature.

    Meat science·2020
    Same author

    Retroviral infection of accessory cells and the immunological paradox in AIDS.

    Immunology today·2014
    Same author

    Clinical immunology in Australia.

    Immunology today·2014
    Same author

    A novel method of measuring the melting point of animal fats.

    Journal of animal science·2014
    Same author

    Merkel cell carcinoma in Western Australia: a population-based study of incidence and survival.

    The British journal of dermatology·2011
    Same author

    Evaluation of the class II region of the major histocompatibility complex of the greyhound with the genomic matching technique and sequence-based typing.

    Tissue antigens·2008

    Area of Science:

    • Immunology
    • Infectious Diseases
    • Dermatology

    Background:

    • Cryptococcosis is a fungal infection typically affecting immunocompromised individuals.
    • Squamous cell tumors are a type of skin cancer.

    Observation:

    • A 54-year-old male presented with multiple squamous cell tumors.
    • The patient also had a bone infection with capsule-deficient cryptococcosis.

    Findings:

    • Severe defect in cell-mediated immunity was identified.
    • Serum antinuclear factor was present.
    • The cryptococcal infection was confined to bone.

    Implications:

    • An underlying T-cell defect may explain the unusual presentation of cryptococcosis.
    • The T-cell defect could also be linked to the aggressive behavior of the skin tumors.
    • This case highlights the complex interplay between immune status and opportunistic infections/neoplasms.

    Related Experiment Videos