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[Osteoarticular infections due to Gram-negative bacilli]
Revue Du Rhumatisme Et Des Maladies Osteo-Articulaires
|February 1, 1981
Summary
Gram-negative bacillary infections, including septic arthritis and spondylodiscitis, represent 11.4% of non-tuberculous osteo-arthritis cases in adults. Early detection and antibiotic sensitivity testing are crucial due to infection severity.
Area of Science:
- Rheumatology
- Infectious Diseases
- Microbiology
Background:
- Non-tuberculous osteo-arthritis in adults can be caused by bacterial infections.
- Gram-negative bacilli are a significant, though not currently progressing, cause of these infections.
Purpose of the Study:
- To determine the frequency of gram-negative bacillary infections in adult non-tuberculous osteo-arthritis.
- To analyze the types of infections (septic arthritis, spondylodiscitis) and causative bacteria.
- To highlight the clinical significance and need for prompt diagnosis.
Main Methods:
- A survey was conducted across 20 French rheumatology units.
- Data was collected on 1,202 cases of adult non-tuberculous osteo-arthritis.
- Infections caused by gram-negative bacilli were identified and categorized.
Main Results:
- 137 cases (11.4%) of gram-negative bacillary infections were identified.
- These included 64 cases of spondylodiscitis and 73 cases of septic arthritis.
- Escherichia Coli, Pseudomonas, and other enterobacteria were the primary pathogens. Infection rates were 9.2% for arthritis and 15.6% for spondylodiscitis.
Conclusions:
- Gram-negative bacilli are a notable cause of osteo-arthritis, particularly spondylodiscitis and septic arthritis.
- Despite not appearing to progress currently, these infections are severe, leading to functional impairment and mortality.
- Routine screening for these bacilli and antibiotic sensitivity testing are essential for effective management.