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Trigeminal deafferentation and ingestive behavior in rats

Journal of Comparative and Physiological Psychology

|April 1, 1981

Summary

Oral somatosensory input is critical for controlling ingestive behavior. Trigeminal deafferentation in rats caused severe deficits in food and water intake, demonstrating the importance of oral sensation.

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Area of Science:

Neuroscience
Behavioral Neuroscience
Physiology

Background:

Ingestive behavior is crucial for survival.
Orosensory input from the oral cavity plays a role in regulating food and water intake.
The trigeminal nerve mediates somatosensory information from the face and mouth.

Purpose of the Study:

To investigate the role of orosensory input in the control of ingestive behavior.
To determine the effects of trigeminal deafferentation on food and water intake in rats.

Main Methods:

Rats underwent selective sectioning of somatosensory trigeminal branches, leaving taste and motor innervation intact.
Varying degrees of deafferentation were performed, affecting different parts of the oral cavity.
Feeding patterns and body weight changes were analyzed.

Main Results:

Severe intake deficits, including aphagia and adipsia, were observed.
Deficits were proportional to the extent of deafferentation, with more severe effects when both upper and lower oral regions were impacted.
Despite impaired consummatory responses, basic actions like biting and chewing remained intact.

Conclusions:

Oral somatosensory input is essential for regulating ingestive behavior.
Trigeminal deafferentation significantly disrupts the control of food and water intake.
The findings highlight the critical role of oral sensation in maintaining normal feeding patterns.

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