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Sclerosing granuloma inguinale

S Subramanian

    The British Journal of Venereal Diseases
    |June 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    A penile sore in a young male was diagnosed as sclerosing granuloma inguinale, also known as donovanosis. The lesion healed effectively with co-trimoxazole treatment.

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    Area of Science:

    • Dermatology
    • Infectious Diseases
    • Urology

    Background:

    • Sclerosing granuloma inguinale, or donovanosis, is a chronic granulomatous sexually transmitted infection.
    • It is caused by the bacterium Klebsiella granulomatis (formerly Calymmatobacterium granulomatis).
    • The disease is endemic in certain tropical and subtropical regions, including parts of India, South America, and Africa.

    Observation:

    • A 21-year-old European male presented with a penile sore lasting two months.
    • Physical examination revealed a penile lesion consistent with granulomatous inflammation.
    • Microscopic examination of a tissue smear from the lesion identified Donovan bodies.

    Findings:

    • The presence of Donovan bodies confirmed the diagnosis of donovanosis.

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  • The patient's penile sore healed completely following a course of co-trimoxazole therapy.
  • Sclerosing granuloma inguinale was the final clinical diagnosis.

    • Implications:

    • This case highlights the importance of recognizing donovanosis in non-endemic areas.
    • Prompt diagnosis and appropriate antibiotic treatment, such as co-trimoxazole, are crucial for successful management.
    • Early intervention can prevent complications and transmission of this sexually transmitted infection.