Alpha-1-antitrypsin (Pi) types in Korean and Chinese populations

Alpha-1-1-antitrypsin phenotypes were determined by isoelectric focusing in 270 Koreans and 52 Chinese. The frequencies of the major alleles were the following, numbers for the Chinese sample are in parentheses: PiM1: 0.65 (0.66), PiM2: 0.22 (0.25), PiM3: 0.06 (0.09). Other alleles, including PiZ were present in low frequencies. The Koreans appear to be quite similar to the Chinese in this system.