Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A boundary method for attenuation correction in positron computed tomography

S C Huang, R E Carson, M E Phelps

    Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
    |July 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Urban runoff as a source of polycyclic aromatic hydrocarbons to coastal waters.

    Environmental science & technology·2012
    Same author

    Field and laboratory methods for investigating a marine gasoline spill.

    Environmental science & technology·2012
    Same author

    Effects of ethanol on axon outgrowth and branching in developing rat cortical neurons.

    Neuroscience·2008
    Same author

    Novel insertional presenilin 1 mutation causing Alzheimer disease with spastic paraparesis.

    Neurology·2004
    Same author

    Dual-[11C]tracer single-acquisition positron emission tomography studies.

    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism·2001
    Same author

    Alzheimer's disease versus dementia with Lewy bodies: cerebral metabolic distinction with autopsy confirmation.

    Annals of neurology·2001
    Same journal

    Overall Survival with [<sup>177</sup>Lu]Lu-PSMA-617 Versus [<sup>177</sup>Lu]Lu-PSMA I&T: A Propensity Score-Matched Real-World Analysis.

    Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
    Same journal

    Toward a Biopsy-Free Diagnosis of Prostate Cancer: Potential of Combined <sup>18</sup>F-Flotufolastat PSMA PET and mpMRI.

    Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
    Same journal

    PSMA PET/CT-Targeted Biopsy in Men with Negative or Equivocal Multiparametric MRI and Exploratory Dynamic Total-Body PET: The FUPERMAN Study.

    Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
    Same journal

    Erratum.

    Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
    Same journal

    Live from 2026 SNMMI Annual Meeting in Los Angeles!

    Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
    Same journal

    CAR T-Cell Therapy for Cancer: Updates and Challenges for Response Assessment.

    Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
    See all related articles

    A novel positron computed tomography (PCT) method improves image quality by accurately calculating attenuation correction factors (ACF) using short transmission scans and edge-finding techniques, reducing noise and scan times.

    Area of Science:

    • Medical Imaging
    • Nuclear Medicine
    • Image Processing

    Background:

    • Positron Computed Tomography (PCT) imaging quality is often limited by artifacts from inaccurate attenuation correction.
    • Existing methods for attenuation correction can be time-consuming or less accurate, impacting diagnostic utility.

    Purpose of the Study:

    • To develop and validate a new, efficient method for attenuation correction in PCT imaging.
    • To improve the accuracy of attenuation correction factors (ACF) and reduce image noise.

    Main Methods:

    • A novel attenuation correction method utilizing short transmission scans and edge-finding algorithms to delineate tissue boundaries.
    • Calculation of ACFs based on identified boundaries and average attenuation coefficients within regions.
    • Validation using computer simulations, phantom studies, and patient data.

    Related Experiment Videos

    Main Results:

    • The new method effectively reduces random noise in transmission measurements.
    • It provides more accurate ACFs compared to traditional geometric correction methods.
    • Demonstrated improvement in the overall quality of PCT images.

    Conclusions:

    • The developed method offers a significant advancement in PCT attenuation correction.
    • Shortened scan times and reduced patient inconvenience are key benefits.
    • Enhanced image quality leads to improved diagnostic capabilities in PCT.