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Thyroid function in hepatic schistosomiasis

M H Fahmy, M Said, F Amara

Annals of Tropical Medicine and Parasitology

|August 1, 1978

Summary

Hepatosplenic schistosomiasis did not significantly alter thyroid hormone levels in men. Thyroid function, including thyroxine and tri-iodothyronine, showed no correlation with liver function or protein levels in affected individuals.

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Area of Science:

Endocrinology
Infectious Diseases
Hepatology

Background:

Hepatosplenic schistosomiasis is a significant parasitic disease affecting the liver and spleen.
Thyroid dysfunction can occur in various chronic illnesses, necessitating investigation in schistosomiasis.

Purpose of the Study:

To investigate thyroid hormone levels in men with hepatosplenic schistosomiasis.
To determine if thyroid function correlates with liver function or serum protein levels in this population.

Main Methods:

Assessed serum thyroxine (T4), tri-iodothyronine uptake (T3-uptake), and free thyroxine index.
Compared values between 17 men with hepatosplenic schistosomiasis and 10 healthy controls.
Analyzed correlations with serum protein levels and liver function tests.

Main Results:

No significant differences were observed in T4, T3-uptake, or free thyroxine index between patients and controls.
Thyroid hormone levels did not correlate with serum protein concentrations.
No correlation was found between thyroid function tests and liver function tests.

Conclusions:

Hepatosplenic schistosomiasis in men does not appear to cause significant alterations in thyroid hormone levels.
Thyroid function in this condition is independent of liver function and serum protein status.

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