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A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
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[Pancreatitis in infants with a clinical diagnosis of septicemia]

L Vega Franco, A García Aranda, C Meza Camacho

    Boletin Medico Del Hospital Infantil De Mexico
    |January 1, 1981
    PubMed

    Insights

    Septicemia in infants can lead to acute pancreatitis. Elevated serum lipase levels in infants with septicemia suggest this complication, while amylase levels remain normal.

    Area of Science:

    • Pediatrics
    • Gastroenterology
    • Infectious Diseases

    Background:

    • Sepsis can trigger systemic complications.
    • Pancreatitis is a potential, though less common, complication of sepsis.

    Observation:

    • Ten infants diagnosed with septicemia were monitored.
    • Clinical symptoms and serum enzyme levels (lipase and amylase) were tracked over seven days.

    Findings:

    • Six out of ten infants exhibited significantly elevated serum lipase activity.
    • Serum amylase levels remained within normal ranges, with a slight decrease noted in some cases.

    Implications:

    • Elevated serum lipase may indicate acute pancreatitis in infants with septicemia.
    • Further investigation into lipase as a marker for pancreatitis in septic infants is warranted.

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