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Central nervous system leukemia and lymphoma: computed tomographic manifestations
AJR. American Journal of Roentgenology
|December 1, 1981
Summary
Computed tomography (CT) detected brain abnormalities in 31 of 405 leukemia or lymphoma patients, including neoplastic masses and hemorrhage. CT findings correlated with clinical and cerebrospinal fluid results, aiding diagnosis and treatment monitoring.
Area of Science:
- Neurology
- Oncology
- Radiology
Background:
- Brain complications are common in patients with leukemia and lymphoma.
- Computed tomography (CT) is a key imaging modality for evaluating these complications.
Purpose of the Study:
- To analyze the spectrum of CT findings in patients with leukemia or lymphoma.
- To correlate CT findings with clinical and cerebrospinal fluid (CSF) data.
Main Methods:
- Retrospective review of CT scans in 405 patients with leukemia or lymphoma.
- Categorization of abnormalities including neoplastic masses, hemorrhage, abscess, and leukoencephalopathy.
- Comparison of CT results with CSF cytology and clinical information.
Main Results:
- CT abnormalities were found in 31 patients (7.7%).
- Neoplastic masses were the most common finding (15 cases).
- CT correctly identified abnormalities in some patients with normal CSF cytology, while being normal in others with diagnosed meningeal disease.
Conclusions:
- CT plays a crucial role in diagnosing and monitoring brain abnormalities in leukemia and lymphoma.
- CT findings can indicate disease progression or response to therapy.
- Integration of CT, CSF analysis, and clinical data is essential for comprehensive patient management.