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Peptostreptococcal endophthalmitis with a relapsing course
Archives of Ophthalmology (Chicago, Ill. : 1960)
|October 1, 1978
Summary
Posttraumatic endophthalmitis caused by Peptostreptococcus relapsed twice despite antibiotics. Vitrectomy led to significant visual recovery, demonstrating its effectiveness in treating this challenging infection.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Microbiology
Background:
- Posttraumatic endophthalmitis is a severe intraocular infection following eye trauma.
- Peptostreptococcus, a Gram-positive anaerobe, can cause serious ocular infections.
Observation:
- A case of posttraumatic exogenous endophthalmitis caused by Peptostreptococcus is presented.
- The infection exhibited bacteriologic and clinical relapse despite standard antimicrobial therapy.
- A second relapse occurred even after apparent sterilization of the vitreous with intravitreal antibiotics.
Findings:
- Peptostreptococcus was isolated in pure culture from the vitreous humor.
- Conventional antimicrobial routes were ineffective in preventing relapse.
- Intravitreal antibiotics did not prevent a second clinical relapse.
Implications:
- Vitrectomy demonstrated an impressive therapeutic response in this refractory case.
- Surgical intervention, such as vitrectomy, may be crucial for managing recurrent endophthalmitis.
- Complete visual recovery to 20/20 was achieved postoperatively, highlighting the efficacy of vitrectomy.