Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Volume determinations using computed tomography

R S Breiman, J W Beck, M Korobkin

    AJR. American Journal of Roentgenology
    |February 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Noise considerations of optical beam recording.

    Applied optics·2010
    Same author

    Immunomodulatory effects of mixed hematopoietic chimerism: immune tolerance in canine model of lung transplantation.

    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2009
    Same author

    Atlantic forcing of persistent drought in West Africa.

    Science (New York, N.Y.)·2009
    Same author

    Review of wheat improvement for waterlogging tolerance in Australia and India: the importance of anaerobiosis and element toxicities associated with different soils.

    Annals of botany·2008
    Same author

    Simplifying the exploration of volumetric images: development of a 3D user interface for the radiologist's workplace.

    Journal of digital imaging·2007
    Same author

    Patterns of peroxidative ethane emission from submerged rice seedlings indicate that damage from reactive oxygen species takes place during submergence and is not necessarily a post-anoxic phenomenon.

    Planta·2006
    Same journal

    The Banality of Cancer: Entropy As a Third Pillar of Lung Nodule Risk Assessment.

    AJR. American journal of roentgenology·2026
    Same journal

    A Narrow Window for Artificial Intelligence-Generated Synthetic Temporal Bone CT From MRI.

    AJR. American journal of roentgenology·2026
    Same journal

    From Uncertainty to Actionable Management: The Isolated Abnormal Axillary Lymph Node.

    AJR. American journal of roentgenology·2026
    Same journal

    Beyond Detection: Translating Artificial Intelligence-Driven Opportunistic Screening Into Clinical Action.

    AJR. American journal of roentgenology·2026
    Same journal

    Navigating PSMA PET Radiopharmaceuticals: Clinical and Operational Factors.

    AJR. American journal of roentgenology·2026
    Same journal

    From Mesenteric Ischemia to Intestinal Stroke.

    AJR. American journal of roentgenology·2026
    See all related articles

    Computed tomography (CT) provides accurate noninvasive volume estimation. The summation-of-areas technique with 2 cm scan spacing offers practical accuracy comparable to complex methods for organs like kidneys and spleens.

    Area of Science:

    • Medical Imaging
    • Radiology
    • Biomedical Engineering

    Background:

    • Accurate noninvasive estimation of in vivo organ volumes is crucial for clinical assessment.
    • Computed tomography (CT) is a leading imaging modality for volumetric analysis.

    Purpose of the Study:

    • To evaluate the accuracy of different mathematical techniques for calculating organ volumes using CT scans.
    • To determine the most practical and accurate method for noninvasive volume estimation.

    Main Methods:

    • CT scans were acquired from phantoms, dog kidneys, and human spleens.
    • Cross-sectional areas were calculated from CT slices.
    • Volumes were determined using four mathematical integration techniques, including summation-of-areas.
    • CT-derived volumes were compared against water displacement measurements.

    Related Experiment Videos

    Main Results:

    • The summation-of-areas technique with 2 cm scan spacing demonstrated accuracy comparable to more complex methods.
    • Mean percentage errors for volume calculations using summation-of-areas were low: 4.95% (phantoms), 3.86% (dog kidneys), 3.59% (human spleens at 1 cm), and 3.65% (human spleens at 2 cm).
    • Manual boundary tracking, not patient factors, represented a more significant source of error.

    Conclusions:

    • The summation-of-areas technique using CT scans at 2 cm intervals is a simple, practical, and accurate method for estimating in vivo organ volumes.
    • CT-based volumetric analysis offers a reliable noninvasive alternative to traditional methods.
    • Improving manual segmentation accuracy is key to further enhancing CT-based volume estimation precision.