Peripheral blood T lymphocytes in patients with duodenal ulcers treated with cimetidine

The influence of cimetidine on the numbers of circulating T lymphocytes was studied in 24 patients with duodenal ulcer treated with cimetidine. The patients were divided into two groups according to the way of cimetidine administration and T lymphocytes were measured during treatment. No significant difference in the numbers of T lymphocytes was found in both groups of patients suggesting that cimetidine given therapeutically has no effect on circulating T lymphocytes.