Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cholescintigraphy in extrahepatic biliary obstruction

W C Klingensmith, C C Kuni, A R Fritzberg

    AJR. American Journal of Roentgenology
    |July 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Radionuclide imaging of hepatic and biliary disease.

    Seminars in liver disease·2001
    Same author

    Comparison of full-field digital mammography with screen-film mammography for cancer detection: results of 4,945 paired examinations.

    Radiology·2001
    Same author

    Association of mammographically defined percent breast density with epidemiologic risk factors for breast cancer (United States).

    Cancer causes & control : CCC·2000
    Same author

    Comparative value of 99mTc-sestamibi scintimammography and sonography in the diagnostic workup of breast masses.

    AJR. American journal of roentgenology·2000
    Same author

    Cure of human carcinoma xenografts by a single dose of pretargeted yttrium-90 with negligible toxicity.

    Proceedings of the National Academy of Sciences of the United States of America·2000
    Same author

    Association of diet and mammographic breast density in the Minnesota breast cancer family cohort.

    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology·2000

    Etiology significantly impacts hepatobiliary imaging findings in extrahepatic biliary obstruction. Cancerous causes often show complete obstruction and reduced hepatocyte clearance, unlike non-cancerous causes.

    Area of Science:

    • Hepatobiliary Imaging
    • Gastroenterology
    • Diagnostic Radiology

    Background:

    • Extrahepatic biliary obstruction is a critical condition requiring accurate diagnosis.
    • Cholescintigraphy (hepatobiliary scintigraphy) is a key imaging modality for evaluating biliary obstruction.
    • Differentiating the etiology of obstruction is crucial for patient management.

    Purpose of the Study:

    • To retrospectively evaluate the effect of obstruction etiology on cholescintigraphy findings.
    • To compare imaging characteristics between cancerous and non-cancerous causes of extrahepatic biliary obstruction.

    Main Methods:

    • Retrospective analysis of 29 patients with extrahepatic biliary obstruction.
    • Review of cholescintigraphy findings, including degree of obstruction and hepatocyte clearance.

    Related Experiment Videos

  • Categorization of obstruction etiology into cancer, cholelithiasis, pancreatitis, and abscess.

    • Main Results:

    • Patients with cancer-related obstruction (n=11) frequently showed complete obstruction (78%) and moderate to severe hepatocyte clearance reduction (82%).
    • Patients with cholelithiasis-related obstruction (n=12) less commonly had complete obstruction (36%) and typically exhibited normal or mild hepatocyte clearance reduction (p<0.05).
    • Obstruction due to pancreatitis (n=5) or abscess (n=1) presented with mild partial obstruction and normal to mildly decreased hepatocyte clearance.

    Conclusions:

    • Etiology significantly influences cholescintigraphy findings in extrahepatic biliary obstruction.
    • Distinct imaging patterns observed can aid in differentiating cancerous from non-cancerous causes.
    • Hepatobiliary imaging provides valuable insights into the underlying cause of biliary obstruction.