Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Longitudinal study of lung function in coal-miners

R G Love, B G Miller

    Thorax
    |March 1, 1982
    PubMed
    Summary

    Coal miners exposed to respirable dust experienced accelerated lung function decline over 11 years. Cumulative dust exposure, not concurrent exposure, was linked to reduced forced expired volume in one second (FEV1).

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Letters.

    The Physician and sportsmedicine·2016
    Same author

    Mathematical Modeling to Predict the Responses to Poorly Soluble Particles in Rat Lungs.

    Inhalation toxicology·2015
    Same author

    Femoroacetabular impingement osteoplasty: is any resected amount safe? A laboratory based experiment with sawbones.

    The bone & joint journal·2015
    Same author

    Impact of diet composition on ileal digestibility and small intestinal morphology in early-weaned pigs fitted with a T-cannula.

    Animal : an international journal of animal bioscience·2012
    Same author

    Development of a Task-Exposure Matrix (TEM) for Pesticide Use (TEMPEST).

    The Annals of occupational hygiene·2010
    Same author

    A review of the data quality and comparability of case-control studies of low-level exposure to benzene in the petroleum industry.

    International archives of occupational and environmental health·2009

    Area of Science:

    • Occupational Medicine
    • Respiratory Epidemiology
    • Environmental Health

    Background:

    • Coal mining is associated with respiratory diseases.
    • Previous studies suggested a link between dust exposure and lung function decline.
    • Direct longitudinal measurement of this relationship in miners was needed.

    Purpose of the Study:

    • To quantify longitudinal lung function loss in coal miners.
    • To correlate lung function decline with individual respirable dust exposure.
    • To validate previous cross-sectional findings with direct measurements.

    Main Methods:

    • Longitudinal analysis of forced expired volume in one second (FEV1) over ~11 years.
    • Data from 1677 coal miners across five British collieries.
    • Comparison with measured concurrent and estimated previous cumulative respirable dust exposures, adjusting for age, height, and smoking.

    Main Results:

    • Lung function loss (FEV1) increased significantly with prior cumulative dust exposure.
    • This association remained after accounting for age, height, smoking, and colliery variations.
    • Concurrent dust exposure showed a relationship with FEV1 only when colliery differences were disregarded.

    Conclusions:

    • Cumulative respirable dust exposure is a significant factor in long-term lung function decline in coal miners.
    • Direct measurement confirms the detrimental impact of dust on miners' respiratory health.
    • Findings support the need for robust dust control measures in mining environments.

    Related Experiment Videos