Secondary structure prediction of sauvagine, a novel biologically active polypeptide from a frog

The secondary structure of sauvagine has been predicted by the statistical method of Chou & Fasman. The results are compared with those obtained by the analysis of the secondary structure of the corticotropin releasing factor. The pattern of helices and beta-turns within these polypeptides is similar. Thus there is an evolutionary relationship in both sequence and secondary structure between these polypeptides, in accordance with their pharmacological properties.