[Non-steroidal antirheumatic agents - questions of the clinician to the pharmacologist]

The problems of clinical application and effects of the non-steroidal antirheumatic drugs have been critically described and pointed at known pharmacological data and clinical publications. Especially still not sufficiently examined connections are emphasized, because their examination could contribute to an aimed use of the antirheumatic drugs. Furthermore the existing declarations concerning the clinical efficacy and the comparison of the effects are critically discussed with regard to their validity. Suitable presuppositions for subsequent trials and for the interpretation of their results are given.