Related Experiment Video
Updated: Aug 12, 2026

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
Published on: June 28, 2021
[Role of intestinal hormones in the pathogenesis of experimental pancreatitis]
Abstract:
In acute experiments on dogs with preliminarily induced pancreatitis the authors traced disturbances of the secretory reactions of the pancreas in response to adequate stimulation with the intestinal hormones. There was a reduction in the activity of complex intestinal hormones preparations obtained from the duodenal mucosa at the acute period of the disease in these dogs. In chronic experiments there was found an increase of acid production debit in the stomach and a shift in the duodenal contents reaction in the acid direction in pancreatitis. A conclusion was drawn on an important pathogenetic role played by the intestinal hormones in the mechanism of disturbances of the pancreatic exocrine secretion in pancreatitis.
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Acute Pancreatitis I: Introduction
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Acute Pancreatitis I: Introduction
Acute Pancreatitis II: Pathophysiology
Chronic Pancreatitis I: Introduction
Chronic Pancreatitis II: Pathophysiology

