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Related Experiment Videos

Depression secondary to cancer

F Petty, R Noyes

    Biological Psychiatry
    |December 1, 1981
    PubMed
    Summary

    Depression is a common psychiatric complication for cancer patients, affecting 17-25% of those hospitalized. Effective treatment requires careful assessment and may involve medication, psychotherapy, and other techniques.

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    Area of Science:

    • Oncology
    • Psychiatry
    • Cancer Care

    Background:

    • Depression is the most frequent psychiatric complication in cancer patients.
    • 17-25% of hospitalized cancer patients experience depression severe enough for intervention.
    • Depression in cancer is often reactive, linked to illness severity and treatment.

    Purpose of the Study:

    • To review the prevalence, etiologic factors, and treatment of depression in cancer patients.
    • To highlight the need for further research and controlled trials.

    Main Methods:

    • Literature review of existing surveys and studies on cancer-related depression.
    • Analysis of psychological, physical, and treatment-related factors contributing to depression.
    • Discussion of current and needed treatment modalities.

    Main Results:

    • Depression is common, reactive, and associated with severe illness.
    • Etiologic factors include psychological reactions, physical distress, metastases, paraneoplastic syndromes, metabolic disturbances, and treatment side effects (surgery, radiation, chemotherapy, hormone therapy).
    • Suicide risk is increased but actual self-destruction is rare.

    Conclusions:

    • Treatment should involve careful assessment to identify specific mechanisms.
    • Treatment options include antidepressant drugs, psychotherapy, and adjunctive techniques.
    • Urgent need for controlled trials using adequate diagnostic criteria for pharmacologic and nonpharmacologic treatments.

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