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A Mouse Model for Chronic Pancreatitis via Bile Duct TNBS Infusion
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Drug-induced pancreatitis: a critical review

A Mallory, F Kern

    Gastroenterology
    |April 1, 1980
    PubMed

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    Chronic pancreatitis is a long-standing, relapsing inflammation of the pancreas, characterized by irreversible damage to the gland. It results in progressive destruction of the pancreatic parenchyma, fibrosis, and eventual loss of both exocrine and endocrine function. The disease may evolve gradually after multiple episodes of acute pancreatitis or develop independently.EtiologyChronic pancreatitis can arise from a variety of causes:Alcohol use is the leading cause, accounting for 70–80% of...
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