The National Large Bowel Cancer Project: a progress report

The progress report from the National Large Bowel Cancer Project updates the state of the art of investigations concerning causes, role of animal models, early diagnosis of disease including potential biochemical markers, genetic and pharmacological consideration, proventive measures, and new approaches to the treatment of large bowel cancer. It points out the many interrelations in the multidisciplinary approaches to understanding the mechanisms of disease, means of prevention, methods of earlier diagnosis, and development of rational approaches in the control of large bowel cancer.